Other Personnel: Manager / Postdocs / Grad Students / Undergrads

Joseph M Wallace, Ph.D.

Joseph Wallace Professor and Chair
Department of Biomedical Engineering
Purdue School of Engineering and Technology
Indiana University-Purdue University at Indianapolis

Department of Orthopaedic Surgery (Adjunct)
Indiana University School of Medicine


jmwalla@iupui.edu
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Overall Research Interests:
Professional Experience:

2020 - Chair, Department of Biomedical Engineering, IUPUI
2020 - Professor, Department of Biomedical Engineering, IUPUI
Graduate Program Faculty, Weldon School of Biomedical Engineering, Purdue University
2020 - Professor, Department of Orthopaedic Surgery (Adjunct)
Indiana University School of Medicine
2016 - 2020 Associate Professor, Department of Biomedical Engineering, IUPUI
Graduate Program Faculty, Weldon School of Biomedical Engineering, Purdue University
2016 - 2020 Associate Professor, Department of Orthopaedic Surgery (Adjunct)
Indiana University School of Medicine
2013 - 2016 Assistant Professor, Department of Orthopaedic Surgery (Adjunct)
Indiana University School of Medicine
2010 - 2016 Assistant Professor, Department of Biomedical Engineering, IUPUI
Graduate Program Faculty, Weldon School of Biomedical Engineering, Purdue University
2007 - 2010 Postdoctoral Fellow, Department of Chemistry, University of Michigan
Michigan Nanotechnology Institute for Medicine and Biological Sciences
2004 - 2007 Ph.D., Department of Biomedical Engineering, University of Michigan
2002 - 2004 M.S., Department of Biomedical Engineering, University of Michigan
1997 - 2002 B.S., Department of Aerospace Engineering, Georgia Institute of Technology
Recent Honors and Awards:
2021 Fellow, American Society for Bone and Mineral Research (ASBMR)
2021 Abraham M. Max Distinguished Professor Award
2019 VA Intramural Non-Clinician Scientist Program
2019 Kathryn J. Wilson Award for Outstanding Leadership and Mentoring of Undergraduate Research
2019 IUPUI Digital Faculty Fellow, Inaugural Class
2018 IUPUI Trustees' Teaching Award
2015 Featured investigator in the 2014 IUPUI Research Report
Current Research Support:
Indiana Center for Musculoskeletal Health Pilot Grant (multi-PI; 0.0 academic months)
Regulation of osteocyte connectivity and bone health by Kalirin
10/01/2021 - 09/30/2022

VA Merit Award, I01 BX005154 (Co-I; 0.5 academic months)
Skeletal complications to a TREM2 variant associated with Alzheimer's Disease
07/01/2021 – 06/30/2025

VA Merit Award, I01 BX003025 (Co-I; 1.2 academic months)
Treating bone deterioration associated with chronic kidney disease
01/01/2021 – 12/31/2025

IUPUI Office of Academic Affairs Department Enhancement Grant (multi-PI; 0.0 academic months)
Building Toward the Recruitment, Retention and Advancement of a Diverse Biomedical Engineering Faculty at IUPUI
11/01/2020 - 10/31/2022

NSF, 1952993 (multi-PI; 1.0 academic months)
LEAP-HI: Engineering New Solutions to Reduce the Burden of Skeletal Fracture
06/01/2020 – 05/31/2024

NIH/NIDDK, F30 DK121399 (Mentor; 0.0 academic months)
The Effect of Etelcalcetide on Bone-tissue Properties in End Stage Kidney Disease
06/01/2019 – 05/31/2024

Indiana CTSI Grant Linking University-wide Expertise (GLUE) (multi-PI; 0.0 academic months)
Studies of Raloxifene Analogs for Improved Properties of Bone Health
05/01/2019 – 04/30/2022 (NCE)

NIH/NIAMS, R01 AR073739 (Co-I; 1.35 academic months)
The Nmp4 Anti-Anabolic Bone Axis
08/15/2018 – 07/31/2023

NIH/NIAMS, R01 AR072609 (PI; 1 academic, 2 summer months)
Targeting collagen as an interventional approach to improve bone material properties
07/05/2018 – 05/31/2023

Completed Research Support:
IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Developing a Combined Model of Diabetes and Chronic Kidney Disease
06/01/2019 – 05/30/2021 (NCE)

Ralph W. and Grace M. Showalter Research Trust Fund (Co-I; 0.0 academic months)
Mechanisms underlying tendon dysfunction associated with diabetes
07/01/2019 – 06/30/2021 (NCE)

NIH/NICHD, R15 HD090603 (Co-I; 0.0 academic months)
Development and Treatment of Skeletal Deficits in a Down Syndrome Mouse Model
07/01/2017 – 06/30/2020

NIH/NIDDK, R01 DK110871 (Co-I; 0.45 academic months, years 3-4)
Pathogenesis of compromised bone quality and mechanics in chronic kidney disease
07/01/2016 – 06/30/2020

VA Merit Award, I01 BX003025 (Co-I; 1.2 academic months, years 3-4)
Treating bone deterioration associated with chronic kidney disease
07/01/2016 – 06/30/2020

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (PI; 0.0 academic months)
Enhancing collagen hydration as a novel way to improve bone mechanics
09/01/2017 – 8/30/2018

NIH/NIAMS, K25 AR067221 (PI; 7 academic, 2 summer months)
Mechanical Protection of Pathological Collagen Synthesis
07/01/2015 – 06/30/2018

NSF EAGER 1643116 (Co-I; 0.0 academic months)
EAGER: Mechanical size effects and bone failure
07/01/2016 – 06/30/2018

Indiana CTSI Core Facility Pilot Proposal (PI; 0.0 academic months)
Second Harmonic Generation Imaging of Collagen Structure in Bone
09/01/2015 – 08/31/2016

Ralph W. and Grace M. Showalter Research Trust Fund (Co-I; 0.0 academic months)
Enhancing skeletal mechanical properties in Osteogenesis Imperfecta
07/01/2015 – 06/30/2016

NIH/NHLBI, R01 HL126705 (Collaborator, 0.9 academic months)
Analysis of TGFbeta Ligands Function in Heart Development and Disease
04/01/2015 – 01/01/2016

Indiana CTSI Research Invention and Scientific Commercialization (RISC) grant (Co-I; 0.0 academic months)
Novel Pharmacological Treatment of Osteogenesis Imperfecta
09/01/2014 – 08/30/2015

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (Co-I; 0.0 academic months)
High-Performance Liquid Chromatography Fluorescence Detector for Biological Assays
06/2014 - 05/2015

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (Co-PI; 0.0 academic months)
Enhancing bone mechanical properties in osteogenesis imperfecta through combination drug treatment
02/01/2014 – 01/31/2015

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (Co-I; 0.0 academic months)
Biomechanical effects of low-intensity, multi-directional loading on bone and muscle growth
01/01/2014 – 12/31/2014

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Effects of in vivo and ex vivo tibial compression on bone damage accrual and fracture toughness in normal and osteolathyritic mice
01/01/2014 – 12/31/2014

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (PI; 0.0 academic months)
Mechanical Stimulation, Fracture Resistance and Fracture Healing in Bone
01/01/2014 – 12/31/2014

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Nanoscale Structure/Function Relationships in Osteogenesis Imperfecta
07/01/2011 – 06/30/2012

NIH/NIDCR, F32 DE018840 (PI; 12 calendar months)
Investigating Ultrastructural Collagen Changes in Osteogenesis Imperfecta
08/01/2008 – 07/31/2010


Current Professional Memberships:
  • Orthopaedic Research Society (ORS) 2008-current:
  • The American Society for Bone and Mineral Research (ASBMR) 2009-current:
  • Biomedical Engineering Society (BMES) 2009-2015, 2020-current
  • American Society of Mechanical Engineers (ASME) 2021-current



  • Journal Editorial Boards:

    Ad Hoc Journal Reviewer:
    Acta Biomaterialia, ACS Applied Materials & Interfaces, Advances in Manufacturing, Biomedicine and Pharmacotherapy, Bone, Bone Reports, Calcified Tissue International and Musculoskeletal Research, Cell and Tissue Banking, Clinical Reviews in Bone and Mineral Metabolism, Connective Tissue Research, Heliyon, Journal of American Aging Association, Journal of Biomechanical Engineering, Journal of Biomechanics, Journal of Biophotonics, Journal of Bone and Mineral Metabolism, Journal of Bone and Mineral Research, Journal of Dental Research, Journal of Mechanical Behavior of Biological Materials, Journal of Orthopaedic Research, Materials Research Society, Matrix Biology, Micron, Nature, Osteoporosis International, Pediatric Research, Plos One, Proceedings of the National Academy of Sciences, Scanning, Scientific Reports, Stem Cell Research & Therapy, Tissue Engineering, Ultrasonics – Sonochemistry


    Teaching: Note: for more details on these courses, please see my Teaching page.

    Send us a message

    Other ways to reach us

    • Professor
      Joseph Wallace

      jmwalla@iupui.edu

    • BBML: Bone Biology and Mechanics Lab

      bonebiomechanics@gmail.com

    • Phone and fax

      JW Office: (317) 274-2448
      Fax: (317) 278-2455
      Lab: (317) 278-3508

    • Facebook

      BBML on Facebook

    • JW Mailing Address

      723 W. Michigan St. SL220
      Indianapolis, IN 46202
      United States

    • Lab Mailing Address

      350 N. Blackford St. EL221
      Indianapolis, IN 46202
      United States